The genes that make squid eyes also make your legs

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first_img The genes that make squid eyes also make your legs Koenig Lab Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe They were surprised to see the gene regulatory network for sprouting limbs at work in a developing eye. But when they added a chemical called WNT that naturally inhibits this network in many organisms to squid embryos, the lens failed to form, they reported here last month at Evolution 2019, an annual meeting of evolutionary biologists, confirming this limb network is also a lens network. Next, the researchers will peer into exactly what each of these genes is doing to make the lens form. Email Sign up for our daily newsletter Get more great content like this delivered right to you! Country PROVIDENCE—Looking a squid in the eye is eerily like looking in a mirror. Squids, octopuses, and other cephalopods are on a very different part of the tree of life from vertebrates. But both have evolved sophisticated peepers that rely on a lens to focus light and provide excellent vision. This independent evolution of such complexity has puzzled biologists for centuries and has prompted searches for clues about how this might have come about.Evolutionary developmental biologists have now discovered that the genes that guide the initial formation of legs in us and other vertebrates also guide the formation of the squid’s lens (seen in cross section of eye above). The find is yet another example of how nature recruits genes used for one purpose to do another job for the body.The squid lens forms as extra-long membranes jutting out for specialized eye cells overlap to form a tight ball. Our lenses are actually degraded cells themselves packed with a clear protein. To learn how the squid lenses form, these researchers carefully tracked where, when, and which genes turn on and off as embryos of Doryteuthis pealeii, a squid commonly served as fried appetizers, develop. By Elizabeth PennisiJul. 15, 2019 , 11:20 AM Click to view the privacy policy. Required fields are indicated by an asterisk (*)last_img

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